The Science of Skin

The Regenerative Power of Polynucleotides

By Dr. VongaiJune 30, 2025

The Regenerative Power of Polynucleotides

The most sophisticated advancements in aesthetic medicine are those that work in harmony with our body’s own powerful systems. We are moving beyond simply masking concerns and into a new frontier of true skin regeneration. At the forefront of this movement is one of the most exciting treatments available today: Polynucleotides.

What Exactly Are Polynucleotides?

Think of Polynucleotides as a bio-stimulator for your skin cells. They are highly purified fragments of DNA, naturally derived and completely compatible with our own biology. When introduced into the skin via tiny injections, they don't add artificial volume like a traditional filler. Instead, they act as powerful signalling molecules, essentially telling your skin cells to wake up, repair themselves, and behave more youthfully.

The Science: How Do They Rejuvenate the Skin?

The regenerative effects of Polynucleotides are multifaceted, creating a healthier skin environment on several levels:

  • They stimulate fibroblasts: These are the critical cells responsible for producing collagen and elastin. Polynucleotides encourage them to build more of these foundational proteins, resulting in firmer, more elastic skin over time.
  • They provide deep hydration: The molecules have a unique ability to bind water, drawing intense hydration to the skin’s structure. This improves texture and gives the skin a dewy, luminous glow.
  • They have an antioxidant effect: They effectively "scavenge" damaging free radicals, protecting your skin from cellular stress and environmental damage that accelerates ageing.

Is This Treatment Right for You?

Polynucleotides are exceptionally versatile and are ideal for clients looking to address concerns related to skin quality and health, rather than just volume loss. They are a fantastic choice for:

  • Treating fine lines and wrinkles, particularly around the eyes and mouth.
  • Improving skin laxity and crepiness on the face, neck, and décolletage.
  • Restoring hydration and radiance to dull, tired-looking skin.
  • Helping to repair certain types of scarring by stimulating healthy new tissue.

A Philosophy of Regeneration

Ultimately, treatments like Polynucleotides are a perfect expression of my clinical philosophy. We are not just chasing lines; we are investing in the long-term health and resilience of your skin. By awakening its own regenerative potential, we can achieve results that are not only beautiful and elegant but are a true reflection of your skin at its healthiest. To find out if this treatment is part of your personalised journey, I invite you to book a consultation.

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